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glutathione-cleavable linker What Makes a Good for Antibody-Drug Conjugates? Antibody-drug conjugate design and mechanisms –

[DOI] [PMC free article] [PubMed] [Google Scholar] [52].Galanis A, Ma H, Rajkhowa T, Ramachandran A, Small D, Cortes J, Levis M, Crenolanib is a potent inhibitor of FLT3 with activity against resistance-conferring point mutants, Blood, 123 (2014) 94–100

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Metalloproteinase Regulation Perhaps one of the most sophisticated aspects of how copper peptides work is their regulation of metalloproteinases (MMPs), enzymes that break down collagen